RESULTS HIGHLIGHTS:- The Revenue for the year ended 31 December 2025 was approximately HK$3,736.5 million, representing an increase of approximately 11.1% as compared with the same period last year.- The Gross Profit Margin for the year ended 31 December 2025 was approximately 55.8%; the gross profit was approximately HK$2,085.0 million, representing an increase of approximately 15.9% as compared with the same period last year.- The Group’s EBITDA for the year ended 31 December 2025 was approximately HK$938.1 million, representing an increase of approximately 32.4% as compared with the same period last year.- The Group’s net profit for the year ended 31 December 2025 was approximately HK$601.2 million, representing an increase of approximately 47.7% as compared with the same period last year.- Basic earnings per share for the year ended 31 December 2025 amounted to approximately HK63.7 cents, representing an increase of approximately 47.5% as compared with the same period last year.- The Board recommended the payment of a final dividend of HK15.0 cents per ordinary share for the year ended 31 December 2025.- For the year ended 31 December 2025, the Group recorded approximately 1,039,000 cases digital solution cases produced from the Group’s production facilities in Mainland China, Thailand and Vietnam, reflecting an increase of 32.7% as compared with the same period in 2024 as a result of our clients’ continued adoption of intra-oral scanners.HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) - 26 March 2026, Modern Dental Group Limited (“Modern Dental” or “the Group”, stock code: 03600.HK), a leading global dental prosthetic device provider, announces its annual results for the year ended 31 December 2025 (“the year”).During the year ended 31 December 2025, the Group’s multi-dimensional strategies and continuous enhancement of operational efficiency and productivity as supported by the ongoing trend of digitalization in the dental industry have resulted in the Group reporting record revenues, net profit and EBITDA numbers during this period. This occurred in a period of challenging macro-economic environment with general softness in demand for dental procedures and trade war uncertainties. The Group has been proactive in its approach to deal with the unprecedented international trade environment leveraging its international production facilities located in Thailand, Vietnam and Mainland China.The global digitalization trend continues to drive consolidation within the dental prosthetics industry, enabling the Group to further expand its market share. Our ongoing digital transformation initiatives are enhancing both customer and patient experiences while improving operational efficiency, further differentiating the Group from competitors and positioning us to outperform industry peers. The Group’s underlying fundamentals remain solid, and we are well positioned to capitalize on emerging opportunities going forward.European BusinessesDuring the year ended 31 December 2025, the European market recorded a revenue of approximately HK$1,887.0 million, representing an increase of approximately HK$268.0 million as compared with the year ended 31 December 2024. This geographic market accounted for 50.5% of the Group’s total revenue. The increase of revenue from the European market was mainly attributable to the increase in sales order volume driven by the launch of new products, such as digital dentures, and our state-of-the-art digital workflows.The Group has been the frontrunner to provide comprehensive digital solutions offerings, ranging from numerous minimal invasive and aesthetic prosthetic solutions to intra-oral scanners and clear aligners, and is well positioned to capture the opportunities arising from the accelerated digitalization trend of the dental industry. The Group continues to aggressively gain market share from international and domestic competitors through our established dental ecosystem solutions with a focus on education and digitalization, which is available within close proximity to our clients; effectively meeting our clients’ high expectations through our various onshore and offshore resources. The Group is committed and will continue to equip ourselves to provide the state-of-the-art digital solutions offerings to the dental community in the market.North American BusinessesDuring the year ended 31 December 2025, the North American market recorded a revenue of approximately HK$696.4 million, representing a decrease of approximately HK$55.7 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 18.6% of the Group’s total revenue.A significant portion of our business in the North America region comprises higher-end products manufactured domestically by MicroDental Laboratories, Inc. and its subsidiaries (“MicroDental Group”). While demand for discretionary cosmetic treatments remained soft throughout 2025, our centralized digital workflows and network-wide production oversight enabled us to deliver enhanced service quality and operational efficiencies to our North American customers.Our diversified supply bases in the US, China, Vietnam and Thailand continue to provide greater flexibility to navigate US tariff uncertainties — an advantage that sets us apart from competitors. Although digitalization of imported product lines drove growth in mass market cases, implementation of the US tariff in April 2025 introduced new uncertainties and contributed to a slow growth in sales for our import-focused business unit.Greater China BusinessesFor the year ended 31 December 2025, the Greater China market recorded a revenue of approximately HK$615.4 million, representing a decrease of approximately HK$46.8 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 16.5% of the Group’s total revenue.The Mainland China market faced headwinds from the volume-based procurement policies and a prolonged period of intense price competition and the situation started to stabilize in the second half of 2025. This also led to aggressive promotions for dental implant treatments by Mainland China dental clinics in Hong Kong (which experienced a notable decrease in patient visits in Hong Kong). The Group’s has deliberately pivoted away from low-margin segments and stay focused on serving mid- and high-value customers, ensuring long-term sustainable profitability of the Group’s business.The Group is optimistic in its mid/long-term outlook for this market in particular where the latest procurement-related government measures are expected to (i) standardize the pricing of dental prosthetics and develop price transparency, which would level the playing field; (ii) allow the Group’s leading brand name and reputation to be a key consideration for its client and customer; and (iii) have the Group benefit from its large production team and its ability to allocate resources efficiently according to the customer or client.Australian BusinessesFor the year ended 31 December 2025, the Australian market recorded a revenue of approximately HK$289.1 million, representing an increase of approximately HK$24.4 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 7.7% of the Group’s total revenue. The increase in revenue from Australia reflected a strong uptake of new digital products driven by the digitalization trend in dental industry and the revenue contribution from the acquisition of Digital Sleep which is partially offset by the depreciation of AUD against HK$ by 2.4% compared with the year ended 31 December 2024.Through our various brands, which offer onshore-and offshore-made products, at multiple price points ranging from economy and standard to premium/boutique, the Group is able to effectively penetrate the entire Australian market. We have invested in local production capacity to provide faster service to our customers, and to provide choices around where the products are made. The Group is one of the largest players in the Australian market and is a preferred supplier to the major corporate dental groups in the market.Other MarketsOther markets primarily include Thailand, Indian Ocean countries, Malaysia, Taiwan and Singapore. For the year ended 31 December 2025, these markets recorded a revenue of approximately HK$248.9 million, representing an increase of approximately HK$182.4 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 6.7% of the Group’s total revenue. The increase in revenue from Other markets was primarily driven by the revenue contribution from the newly acquired Hexa Ceram.Future Prospects and StrategiesThe global macroeconomic environment remains uncertain, with geopolitical tensions and potential tariff changes continuing to create headwinds. However, the Group’s geographically diversified production footprint and global distribution network position us strongly to navigate these challenges. Unlike many competitors reliant on single-country manufacturing, our operations across China, Vietnam and Thailand (including the newly acquired Hexa Ceram) provide superior resilience and flexibility. This strategy, combined with our ability to adapt quickly to local market conditions, enables the Group to mitigate risks and capitalize on opportunities across regions.The dental industry has continued to demonstrate remarkable resilience, underpinned by irreversible demographic trends, including aging populations and increasing awareness of oral health, which drive consistent long-term demand. Building on our record 2025 performance, the Group is well placed to sustain momentum and further strengthen its market leadership.Digitalization remains an irreversible industry trend that is accelerating consolidation of the dental prosthetics industry. We are at the forefront of this transformation, with digital solution cases now representing approximately 35–40% of total volume. Our centralized digital workflows, intra-oral scanner partnerships, proprietary solutions and global education centers have enhanced operational efficiency, reduced turnaround times and delivered superior customer experiences. These initiatives create high entry barriers and will continue to drive margin expansion and market share gains in the coming years.Following the successful integration of Hexa Ceram (Thailand’s largest dental laboratory, acquired in January 2025) and Digital Sleep Design (Proprietary nylon oral appliance to treat obstructive sleep apnea), our Southeast Asian presence and specialized capabilities have been significantly strengthened. This expansion, coupled with our diversified supply bases in the US, China, Vietnam, and Thailand, provides enhanced flexibility to address potential trade and geopolitical risks while supporting faster regional delivery.Looking ahead, the Group remains committed to reinforcing its worldwide leading position through a multi-dimensional approach. We will continue to pursue selective acquisitions, joint ventures and partnerships to expand and complement our product offerings, particularly in our high-growth clear aligner, Trioclear, while strengthening our distribution and sales networks. Ongoing investments in mass-scale production facilities, AI, automation, research and development, and digital innovation will drive efficiency gains and secure our position at the forefront of the industry.About Modern Dental GroupModern Dental Group Limited (Stock code: 03600.HK) is a leading global dental prosthetics provider, distributor and consultant with a focus on providing custom-made prostheses to customers in the growing prosthetics industry. Our product portfolio is broadly categorized into three product lines: fixed prosthetic devices, such as crowns and bridges; removable prosthetic devices, such as removable dentures; and other devices, such as orthodontic devices, sports guards, clear aligners, and anti-snoring devices. Modern Dental Group has a global portfolio of respected brands, including Labocast, Permadental and Elysee Dental in Western Europe, YZJ Dental in China, Modern Dental Lab in Hong Kong, Modern Dental USA and MicroDental in the United States, Modern Dental Pacific in Australia and New Zealand, Modern Dental SG in Singapore, Modern Dental TW in Taiwan, Apex Digital Dental in Malaysia and Hexa Ceram in Thailand. We have grown these brands by providing premium and consistent quality products and superior customer service. We have more than 80 service centers in over 28 countries and serve over 35,000 customers. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

业绩摘要：- 截至2025年12月31日止年度收益约为37.4亿港元, 同比增加约11.1%。- 截至2025年12月31日止年度毛利率约为55.8% ；毛利约为20.8亿港元，同比增加约15.9%。- 截至2025年12月31日止EBITDA 约为9.4亿港元，同比增加约32.4%。- 本集团于截至2025年12月31日止纯利约为6.0亿港元，同比增加47.7%。- 截至2025年12月31日止每股基本盈利约为63.7港仙，相较去年同期增加约47.5%。- 董事会建议宣派截至 2025年12月31日止年度末期股息每股普通股15.0港仙。- 截至2025年12月31日止年度，本集团于中国内地、泰国及越南生产设施生产之数码化解决方案个案增加至约1,039,000件，较2024年同期增加32.7%，原因为更多客户采用口腔内部扫描仪。香港, 2026年3月27日 - (亚太商讯 via SeaPRwire.com) - 2026年3月26日，全球领先之义齿器材供应商 - 现代牙科集团有限公司 (简称「现代牙科」或「本集团」，股份代号：03600.HK) 欣然公布截至2025年12月31日止年度(「年度」) 业绩。截至2025年12月31日止年度，在牙科行业数码化趋势持续的支持下，本集团的多维度策略及持续提升的营运效率及生产力，使其于本期间的收益、纯利及EBITDA数字均创下纪录新高。虽然期内宏观经济环境充满挑战，牙科手术的需求普遍疲弱，且贸易战存在不确定性，然而仍然创下纪录。本集团利用位于泰国、越南及中国内地的国际生产设施，积极应对前所未有的国际贸易环境。全球数码化趋势持续推动义齿行业的整合，使本集团进一步扩大其市场份额。我们持续的数码转型措施提升客户及病人体验的同时，进一步使本集团在竞争对手中脱颖而出，表现优于同业。本集团的相关基础仍然稳固，并将全力以赴把握未来机遇。欧洲市场业务截至2025年12月31日止年度，欧洲市场录得收益约18.9亿港元，较去年增加约2.7亿港元，此地理市场占本集团收益总额50.5%。欧洲市场收益增加主要由于新产品的推出(例如数码化义齿)及我们最先进的数码化流程，推动销售订单量增加。本集团已成为提供全面数码化解决方案的先驱，范围涵盖多项微创及美容义齿解决方案以至口腔内部扫描仪及透明矫正器，本集团已准备好把握牙科行业数码化趋势加速带来的机遇。本集团继续透过所建立，重点为教育及数码化且非常邻近客户的牙科生态系统解决方案，积极从国际及本地竞争对手取得市场份额；透过不同的境内及境外资源有效地满足我们客户的高期望。本集团一直致力并将继续装备好自己，为市场上的牙科领域提供最先进的数码化解决方案。北美市场业务于截至2025年12月31日止年度，北美市场录得收益约7.0亿港元，较去年减少约5,570万港元，此地理市场占本集团收益总额约18.6%。我们在北美地区的大部分业务包括MicroDental Laboratories, Inc.及其附属公司(「MicroDental集团」)在本地制造的高端产品。虽然2025年对主动美容治疗的需求仍然疲弱，然而我们的中央化数码流程及对区内广泛生产单位的网络让我们为北美客户交出更高服务质素及营运效率。我们位于美国、中国、越南及泰国等地的多元化供应基地，继续在应对美国关税的不确定性时带来更大弹性－此为将我们与竞争对手作区分的优势。虽然进口产品线的数码化带动大型市场个案的增长，然而2025年4月在美国实施的关税带来新的不确定性及为我们以进口为主的业务单位的销售带来缓慢增长。大中华市场业务截至2025年12月31日止年度，大中华市场录得收益约6.2亿港元，较去年减少约4,685万港元，此地理市场占本集团收益总额约16.5%。中国内地市场面对带量采购政策及价格激烈竞争延长的逆境，而于2025年下半年情况开始稳定。此亦导致中国内地牙科诊所积极于香港推广种植牙治疗(香港患者就诊人数明显减少)。本集团有意退出低利润分部，并专注于中及高价值客户，确保本集团业务能够长期及可持续获利。本集团对此市场的中长期前景感到乐观，特别是在政府最新的采购相关措施中，预计(i)规范义齿价格及建立价格透明度，平衡中心点；(ii)让本集团领先的品牌名称及声望成为客户及顾客的主要考虑；及(iii)让本集团从其庞大生产团队中得益及根据顾客或客户有效分配资源的能力。澳洲市场业务截至2025年12月31日止年度，澳洲市场录得收益约2.9亿港元，较去年增加约2,438万港元，此地理市场占本集团收益总额约7.7%。澳洲的收益录得增长，反映牙科行业数码化趋势带动大量新的数码化产品，以及收购Digital Sleep的收益贡献，但部分被相较于截至2024年12月31日止年度，澳元兑港元贬值2.4%所抵销。透过我们不同的品牌(可提供境内及境外制造的产品)，凭借涵盖从经济及标准至优质/精品等的多种价位，本集团能够有效地渗透整个澳洲市场。我们投资于本地产能，以为客户提供更快捷的服务，并可供选择产品之生产地。本集团为澳洲市场最大参与者之一并为市场内主要企业牙科团体的首选供应商。其他市场其他市场主要包括泰国、印度洋国家、马来西亚、台湾及新加坡。截至2025年12月31日止年度，该等市场录得收益约2.5亿港元，较截至2024年12月31日止年度增加约1.8亿港元。此地理市场占本集团收益总额约6.7%。其他市场的收益增加主要由于新收购的Hexa Ceram带来的收益贡献所致。未来前景及策略全球宏观经济环境仍然不明朗，地缘政治的紧张局势及关税的潜在变动继续营造不利环境。然而，本集团的生产遍及全球各地，而全球分销网络让我们在面对该等挑战时享有独特优势。有别于依赖单一国家生产的一众竞争对手，我们的营运遍布中国、越南及泰国(包括新收购的Hexa Ceram)等地，让我们面对挑战时能够进退有据，灵活应变。此策略连同我们快速适应当地市场环境的能力，使本集团降低风险，同时把握各地区的新兴机遇。牙科行业继续展现卓越的适应力，在不可逆转的人口趋势下加以突显，包括人口老化及人们对口腔健康的意识提高，持续带动义齿的长期需求。本集团建基于2025年创记录的表现而处于有利位置，能够保持良好势头，同时进一步强化市场的领导地位。行业数码化势不可挡，加快义齿行业的整合。我们处于转型的尖端，目前数码化解决方案个案占总销量约35至40%。我们的中央化数码工作流程、有关口腔内部扫描仪的伙伴关系、专有的解决方案及全球教育中心有助提升营运效率、缩短处理时间及提供卓越的客户体验。有关措施创造高进入门槛，并将于未来数年继续扩大利润及增加市场份额。在成功整合于2025年1月收购的泰国最大牙科实验室Hexa Ceram及Digital Sleep Design(用于治疗阻塞性睡眠窒息症的专利尼龙口腔矫正器)后，我们在东南亚地区的影响力及专业能力已经大幅提升。是次扩张连同我们位于美国、中国、越南及泰国等地的多元化供应基地，让我们在应对潜在的贸易及其他地缘政治风险时带来更大弹性，同时支持区内快速交付。展望将来，本集团仍然致力透过多角度方针强化其全球领导地位。我们将继续寻求具针对性的收购、合营企业及伙伴关系，以扩大及补充我们所提供的产品，特别是我们高增长的透明矫正器TrioClear，同时加强我们的分销及销售网络。我们在大型生产设施、AI、自动化、研发及数码创新方面的持续投资，使效率大幅增高，从而确保我们一直处于行业尖端。关于现代牙科集团现代牙科集团有限公司 (股份代号: 03600.HK) 为全球领先的义齿器材供应商、经销商和顾问，专注于发展迅速的义齿行业为客户提供定制式义齿。我们的产品组合大致可分为三类﹕固定义齿器材，例如牙冠及牙桥；活动义齿器材，例如活动义齿；及其他器材，例如正畸类器材、透明牙套、运动防护器及防鼾器。 现代牙科集团拥有多个备受称许的全球品牌，包括西欧的Labocast、Permadental及Elysee Dental、中国的洋紫荆牙科器材、香港的现代牙科器材、美国的Modern Dental USA及MicroDental、澳洲及新西兰的Modern Dental Pacific、新加坡的Modern Dental SG、台湾的 Modern Dental TW、马来西亚的 Apex Digital Dental及泰国的Hexa Ceram等。我们提供稳定和优质的产品及卓越的客户服务，令这些公司品牌能茁壮成长。我们于全球超过 28个国家拥有超过 80 家服务中心及服务逾 35,000 名客户。 Copyright 2026 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HIGHLIGHTS:- Total gross billings amounted to approximately RMB3,955.0 million, representing an increase of approximately 12.8% from approximately RMB3,505.9 million for the corresponding period.- Total revenue was approximately RMB3,430.1 million, representing an increase of approximately 48.7% from approximately RMB2,306.0 million for the corresponding period.- The profit attributable to Shareholders of the Group was approximately RMB921.8 million, representing an increase of approximately 238.5% from approximately RMB272.4 million for the corresponding period.- Non-HKFRS adjusted profit for the year (excluding the share-based compensation expenses) was approximately RMB1,022.5 million, representing an increase of approximately 191.8% from approximately RMB350.5 million for the corresponding period.- Taking into account the financial and cash flow positions of the Group, the Board recommends the payment of a final dividend of approximately HKD168.5 million for the year ended December 31, 2025, representing HKD0.36 per share (in cash), and the proposed final dividend is subject to consideration and approval by Shareholders at the AGM.HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) - JF SmartInvest Holdings Ltd (the “Company” ; together with its subsidiaries, the "Group" or “we”) is pleased to announce its consolidated annual results for the year ended December 31, 2025 (the “Reporting Period”). During the Reporting Period, leveraging its “technology + investment research” dual-drive strategy, the Group achieved outstanding performance. Supported by robust cash flow and profitability, the Board has proposed a final dividend of HK$0.36 per share, bringing the total dividend for the full year to approximately HK$407.4 million when combined with the interim dividend already paid, reflecting its commitment to delivering returns to shareholders.Strong Financial Performance with Substantial Profitability ImprovementDuring the Reporting Period, the Group continued to advance product innovation, AI applications, and investment research capabilities, driving solid growth across its business. Total revenue for the year reached RMB3,430.1 million, representing a YOY increase of 48.7%. Gross profit amounted to RMB2,821.0 million, up 48.9% YOY, while the gross profit margin remained at a high level of 82.2%, indicating the favourable economies of scale and earnings quality of the Group’s business model.In terms of profitability, profit attributable to equity shareholders surged by 238.5% YOY to RMB921.8 million. Excluding share-based compensation expenses, non-HKFRS adjusted profit for the year reached RMB1,022.5 million, representing a YOY increase of 191.8%, fully demonstrating the effective strategy execution and market adaptability of the Group.The Group places great emphasis on shareholder returns. The Board recommends the payment of a final dividend of approximately HKD168.5 million for the year ended December 31, 2025, representing HKD0.36 per share (in cash). Together with the interim dividend of approximately HK$238.9 million already distributed, the total dividend for 2025 will amount to approximately HK$407.4 million. The steady dividend policy fully reflects the Group’s ample cash reserves and its firm confidence in future development prospects.Continued Optimisation of Product Matrix and Enhancement of Diversified Service SystemDuring the Reporting Period, the Group continued to build a diversified product matrix, enriching its product portfolio in response to different customer needs. VIP products 'Stock Navigator, Super Investor' were steadily optimized, with the addition of several quantitative products and AI-powered products. We also launched a 24/7 AI intelligent customer service system, which significantly improved service efficiency. The live streaming system was upgraded, with sessions increasing by 36% YOY and average daily unique viewers exceeding 100,000.Relying on an integrated “AI + content + service + tools” solution, the Enjoy-Stock Pad recorded net sales volume exceeding 75,000 units during the Reporting Period. The Jiuyao Stocks launched over 80 lightweight products, converting professional investment research capabilities into standardised products. The SmartInvest APP completed its strategic transformation from a tool to a platform, with monthly active users increasing by more than 40% YOY and the 30-day retention rate remaining above 50%.The Group further enhanced its product matrix with two new products, Decision Master and Star-tier Services, filling the gap in the mid-tier product system and enabling a seamless trading service experience. Decision Master focuses on three AI+ investment research modules - themes, value investing and quantification - comprehensively enhances investment decision-making capabilities of individual investors. Star-tier Services collaborates with multiple securities brokerages and partners to create a fully integrated closed-loop ecosystem of“tools-services-trading”, serving over 50,000 users during the Reporting Period.Guided by Technological Innovation, Striving Towards “Investment Advisory Intelligent Agent 2.0”The Group regards innovation and technological R&D as its core driving force, accelerating its transformation towards “digital intelligence”, and advancing towards the era of “investment advisory intelligent agent 2.0”. During the Reporting Period, R&D expenses amounted to approximately RMB356 million, with R&D personnel reaching 624, a YOY increase of approximately 42.8%. The Group held 158 software copyrights and patents in AI, big data and product features, with 22 new items added on a year-on-year basis.The self-developed FinSphere Agent Large Model Assistant V3.0 passed the Large Model Assistant Functionality Completeness Test conducted by the China Academy of Information and Communications Technology, becoming the first large-model application in the securities industry. During the Reporting Period, it served approximately 664,000 customers with cumulative services of 22.58 million. The digital intelligent investment robo-advisor “Jiu Ge” served approximately 600,000 customers with cumulative services exceeding 19 million. The Group also launched stock diagnosis intelligent agent 4.0, AI Xiaoce Q&A assistant, and established an intelligent compliance and risk control platform covering the entire business workflow, indicating that the group's AI capabilities have gradually been implemented in core scenarios.To strengthen its technological foundation, the Group established a technology subsidiary, Jiufang Zhiqing, and set its foothold in “Shanghai Foundation Model Innovation Center”, China’s first large model innovation ecosystem community. The subsidiary serves as the Group’s core AI vehicle for operating a native service technology system, promoting the deep application of AI in scenarios such as investment research, investor education, and risk control.Deep-Rooted Investment Research as the Cornerstone, Adhering to Buyer-Side Advisory and Deepening the “1+N” Investment Research SystemThe Group continues to deepen its “1 research institute and N business lines” investment research system, with the JF Financial Research Institute as investment research hub. The Institute has established a pyramidal-structured professional talent echelon led by Chief Economist Dr. Xiao Lisheng, comprising 4 experts, 8 super-IPs and 128 professionals. As of the end of the Reporting Period, the Group had 576 employees holding securities investment advisory qualifications and 2,628 employees holding securities practitioners, maintains a leading team scale and structure in the industry.During the Reporting Period, The Institute conducted more than 300 research activities, covering more than 2,000 listed companies. The Institute authored approximately 1,200 in-depth research reports and 45 sets of thematic courses with a total duration of 2,000 minutes, continuously enhancing the professional capabilities of buyer-side consultants.Multi-Dimensional, Full-Funnel Traffic Operation to Unlock New Growth DimensionsDriven by AI technology, the Group positions refined MCN-based traffic operations as a central hub connecting users with its business, building an integrated, synergistic omni-channel traffic ecosystem comprising “public-domain MCN (multi-platform) + private-domain + proprietary APP”. On the technological front, the Group applied AIGC to restructure content production, shifting from manual creation to “human-machine collaboration” model, and established a data flywheel integrating “advertising data, model training and operational automation”. During the Reporting Period, the Group consolidated its leading position on online short-video and live streaming platforms’ operations, established a multi-platform coordinated traffic matrix, and developed a multi-tiered, high-quality content ecosystem. It also pioneered e-commerce models for the Enjoy-Stock Pad and AppStore models for the APP, driving deep integration between traffic operations and product features.Future OutlookMr. Chen Wenbin, chairman of the Board and chief executive officer of JF SmartInvest Holdings Ltd, said: “In 2025, we remained committed to the dual-drive strategy of ‘technology + investment research’. Not only did we achieve leapfrog growth in performance, but we also successfully led the industry into the era of ‘Investment Advisor Agent 2.0’. Leveraging artificial intelligence and big data technologies, we developed AI products such as the JF Robo-Advisor, FinSphere Agent and FinSphere Report, achieving industry-leading innovations and scenario-based applications, helping users accomplish the critical transition from ‘cognitive improvement’ to ‘decision optimisation’. At the same time, we transformed our professional investment research capabilities into easily accessible lightweight services, realising a strategic shift ‘from tool to platform’. We uphold the principles of rational investing, value investing and long-term investing, assisting clients in developing sound investment philosophies.“In the future, the Group will focus on four key strategic dimensions. First, deepening AI-driven empowerment across all scenarios, accelerating the iteration of AI agents and their commercialisation on the consumer side, and driving the Group’s digital and intelligent transformation. Second, leveraging Forthright Securities and Forthright Capital’s licenses, advancing the globalisation strategy by exporting the Jiufang’s core models, accelerating overseas business expansion. Meanwhile, promoting license upgrading and strategic investment layout to further improve the construction of digital asset infrastructure. Third, strengthening product-driven business diversification and synergies, deepening cooperation with licensed financial institutions such as securities brokerages, and building a service closed loop covering pre-investment, in-investment and post-investment. Fourth, continuing to optimize the customer operation system, unlocking the value of traffic through full-funnel traffic initiatives, and achieving long-term customer retention. We are dedicated to making investing simpler and more professional while enhancing investors’ sense of fulfillment in investment and wealth management.”About JF SmartInvest Holdings Ltd (Stock Code: 9636)JF SmartInvest Holdings Ltd is a new generation stock investment assistant. The Company is engaged in the provision of equity investment instruments, securities investment advisory, investor education and other services to individual investors. The products include stock quote software, the AI Stock Machine, Stock Navigator, Super Investor and Jiuyao Stocks. The Company adopts the technology + investment research model, develops JF Robo-Advisor, FinSphere Agent, FinSphere Report and other products based on artificial intelligence (AI) and big data technology, which are applied to the industry in terms of innovative practice and scenario application.For enquiries, please contact:Financial PR (HK) LimitedEmail: ir@financialpr.hkTel: 852 2610 0846Fax: 852 2610 0842 Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

SINGAPORE, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) - Choosing where to place your savings in Singapore is an important financial decision that requires careful consideration. With many banks offering different types of accounts, it is easy to get confused. However, picking the right one is the first step to reaching your financial goals, whether you are saving for a dream wedding, a new home, or a retirement fund.The good news is that you no longer need to spend a whole afternoon waiting at a bank branch. You can now open a bank account online in just a few minutes using your phone or computer. Here is a simple guide to help you choose the best account for your needs in 2026.Identify Your Financial HabitsBefore focusing on interest rates, consider how you manage your money on a daily basis. Savings accounts in Singapore usually fall into two categories:The Active Saver: These accounts give you high interest rates, but you have to make a few mandatory transactions each month. Usually, you need to credit your salary and spend a set amount on your credit card.The Passive Saver: These accounts help you earn bonus interest just for keeping your money in the account and letting it grow. You do not need to worry about credit card spending or paying bills.Compare Interest RatesBefore opening a bank account online, make sure you compare the interest rates. Many basic accounts offer low interest rates. To make your money grow, you should look for bonus interest.For example, a high-interest account can offer between 2% and 5% depending on the rules you follow. If you have SGD 50,000, the difference between a basic account and a high-interest one could be hundreds of dollars in extra cash every year. Always check the effective interest rate, which tells you the real amount you will earn after all the levels are counted.Look for Welcome PromotionsBanks in Singapore are always competing for your business. When you open a bank account online, you can often grab a welcome gift, such as cash credits or rewards. These promotions are a great way to get a head start on your savings. Just make sure to check the dates, as many of these flash deals only last for a few months.Check the Fees and MinimumsEven a great account can lose you money if you are not careful about fees. Before you sign up, check for these three things:Minimum balance: Most accounts require maintaining a certain amount of money in the account at all times. If the balance drops below this limit, the bank may charge you a monthly fee.Initial deposit: Some accounts require at least SGD 1,000 to get started.ATM access: Make sure the bank has plenty of ATMs near your home or office so you do not get charged for using the machine of another bank.Open an Account OnlineOnce you have picked the right account, the final step is to fill out your application. In Singapore, you can use Singpass MyInfo to fill out your application automatically.When you open a bank account online, your details, such as your NRIC, address, and income, are pulled directly from the government database, thus reducing paperwork. Most accounts are approved almost instantly, and you can start using your new digital card right away.Final ThoughtsChoosing a savings account is not just about finding the highest interest rate. It is about finding the one that fits how you live. If you are a busy professional who already uses a credit card, an active account is perfect. If you just want to set your money aside and forget it, a passive account is better.By taking 10 minutes to compare your options today, you can ensure that every dollar you earn works as hard as you do.Disclaimer: This article is for general information only and does not have any regard to the specific investment objectives, financial situation and particular needs of any specific person. The views expressed in this article are solely those of the author. This article shall not be regarded as an offer, recommendation, solicitation or advice. You may wish to consult your own professional advisers about this article, in particular, a financial professional before making financial decisions. Any past events, trends and/or performance referred to in this article may not necessarily be indicative of future events, trends or performance. This article is based on certain assumptions and reflects prevailing conditions as at the time of publication, which are subject to change at any time without notice. The author and publisher of this article as well as any other parties associated with this article make no representation or warranty of any kind, whether express, implied or statutory, in respect of this article and accept no liability or responsibility for the completeness or accuracy of this article or any error, inaccuracy or omission relating to this article and/or any consequence, injury, loss or damage howsoever suffered by any person relating to this article, in particular, arising from any reliance by any person on this article. Publishers or platforms may be compensated for access to third party websites.Contact Information:Name: Sonakshi MurzeEmail: Sonakshi.murze@iquanti.comJob Title: ManagerSOURCE: iQuanti Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Mar 23, 2026 - (ACN Newswire via SeaPRwire.com) – Everest Medicines today announced that it has entered into an Asset Purchase Agreement with Corxel Pharmaceuticals Hong Kong Limited (“CORXEL”). Under the agreement, the Company has acquired the rights to develop, manufacture, and commercialize CARDAMYST™ (etripamil) nasal spray in Greater China, including Chinese Mainland, Hong Kong, Macao and Taiwan region.Under the terms of the agreement, Everest will pay CORXEL an upfront payment of US$30 million (equivalent to approximately RMB344,895,000), as well as potential development milestone payments of up to US$20 million (equivalent to approximately RMB137,958,000). As part of this agreement, Everest will be assigned and transferred rights, interests, claims, duties, obligations and liabilities (other than certain excluded liabilities) under the Milestone License Agreement entered into by CORXEL in May 2021 and certain related ancillary agreements.CARDAMYSTTM (etripamil) nasal spray is a novel, rapid-acting calcium channel blocker as administered as needed via a convenient, portable nasal spray. It offers rapid onset of action, favorable tolerability, and the potential for at-home self-administration, enhancing patient accessibility. In December 2025, CARDAMYST was approved by the U.S. Food and Drug Administration (FDA), becoming the first and only self-administered nasal spray in more than 30 years capable of converting paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm in adults. As a rapid-acting treatment option, CARDAMYST can be self-administered outside the emergency department or other healthcare settings, enabling patients to actively manage episodes and gain greater control over their condition. In addition to its approved indication for PSVT, etripamil nasal spray is also under clinical development for atrial fibrillation with rapid ventricular response (AFib-RVR). Phase II trials have shown encouraging results, and Phase III trials are planned, with the potential to further extend its therapeutic impact to a broader patient population.In China, the New Drug Application (NDA) for etripamil nasal spray was accepted by the National Medical Products Administration (NMPA) on January 17, 2025 and is expected to receive approval in the third quarter of 2026.PSVT is characterized by abnormalities in the heart’s electrical system that cause sudden unexpected and often severely symptomatic episodes of rapid heart rate. There are currently no approved self-administered, fast-acting, non-injectable therapies for acute PSVT, leaving patients with limited treatment options beyond emergency care. Approximately 2.3 to 4 per 1,000 individuals are affected by PSVT, representing an estimated 3 to 6 million patients in China.AFib-RVR is a type of irregular heart rhythm, characterized by an irregular and elevated heart rate. Its onset is typically gradual, episodes are less likely to terminate spontaneously, and the condition tends to recur, significantly increasing the risk of thromboembolism and serious complications such as stroke and heart failure. In China, atrial fibrillation affects an estimated 1.6% of the population, representing nearly 20 million patients, and is expected to increase with an aging population. Both PSVT and AFib-RVR are associated with a loss of control and a significant psychological burden for patients.Overall, the combined patient population for PSVT and AFib-RVR exceeds 25 million, representing a significantly unmet clinical need that urgently requires more convenient and more effective treatment options.In terms of clinical data, the NDA for etripamil nasal spray was accepted by the NMPA based on data from the pivotal global Phase 3 RAPID study and the China Phase 3 JX02002 study. Both trials met their primary endpoints. Overall, the treatment emergent adverse events (TEAEs) were comparable between the etripamil and placebo groups. The FDA approval of CARDAMYST was supported by a robust clinical program that included safety data from more than 1,800 participants across more than 2,000 PSVT episodes. This included the Phase 3 RAPID trial, a global, randomized, double-blind comparison of etripamil versus placebo, published in The Lancet in 2023. The RAPID trial achieved its primary endpoint, with 64% of participants who self-administered etripamil (N=99) converting from supraventricular tachycardia (SVT) to sinus rhythm within 30 minutes compared with 31% on placebo (N=85) (HR = 2.62; p

近日，2026中关村论坛年会在北京隆重举行。作为国家级科技创新交流合作平台的重要参与者，百望股份受邀出席本次国家级科技创新交流盛会，并在"东盟创新合作发展论坛"中发表了重磅主题演讲。论坛上，百望股份聚焦跨境贸易合规痛点，推介全球智能税务合规平台Tax Swift。它内置百望自研的AI税务引擎、百望指数与国家适配器，依托覆盖全球的税务规则知识库，动态监控、AI分析、自动更新，打造起全球贸易的"合规路由器"，为国际经贸合作注入合规新动能。论坛聚焦科技创新，跨境合规成全球贸易核心命题2026年中关村论坛年会，是经国务院批准、以"科技创新与产业创新深度融合"为年度主题，由科技部、国家发展改革委、工业和信息化部、国家国资委、中国科学院、中国工程院、中国科协和北京市政府共同主办。大会汇聚了100多个国家和地区的全球顶尖科学家、企业家及国际组织代表，上千名嘉宾共同搭建起中国与世界科技创新交流的桥梁。作为本次中关村论坛的重要平行论坛，东盟创新合作发展论坛聚焦中国与东盟科技创新协同、产业融合发展、跨境贸易便利化等核心议题，汇聚东盟各国政、产、学、研各界代表，交流研判破解区域经贸合作中的共性难题。在主题演讲环节，百望股份围绕着"AI赋能中企出海：构建全球化合规新底座"展开了深度分享。当前，全球贸易一体化进程不断加快，跨国经营的业务蓬勃发展，但税务合规难题始终是制约全球贸易高效推进的关键瓶颈。尤其是东盟这样的活力经济体，区域内各国经贸往来频繁，跨境交易规模持续攀升，市场主体对于交易效率、交易合规有着更高的需求和更迫切的期待，而区域内各国税务政策、技术标准的差异，却成为了制约中国-东盟跨境贸易提质增效的重要因素。从实践来看，国际贸易税务合规难题呈现多元化、复杂化态势：- 语言与格式壁垒凸显，不同标准、规范让企业票据解读成本高、理解易出偏差；- 各国财税政策碎片化严重，差异性的税种、税率、申报流程，让企业难以精准掌握；- 技术标准不统一，系统接口、数据传输缺乏规范，各类操作繁琐且效率低下；- 跨境交易链条长、涉及主体多，企业难以实现全流程风险检测；这些难题不仅增加了企业跨境经营的成本，更成为制约企业融入全球产业链、拓展国际市场的关键瓶颈。百望股份的Tax Swift平台，正是破解合规困境、保驾跨境贸易的全新技术创新，尤其为中国-东盟跨境贸易合规发展提供了高效可行的思路。Tax Swift重磅亮相，全链路一站式赋能国际贸易合规作为百望股份的深耕全球税务合规领域、布局国际化市场的核心成果，Tax Swift一次适配，就可帮助企业构建起覆盖"票据处理-纳税申报-风险管控"的全链路跨境税务合规服务体系：一是全球AI全链路票据处理能力，可打破语言与格式壁垒。国际化引擎、发票引擎、税务引擎与国家适配器，四重引擎自动协同运转，完成智能算税、智能识别等，一套架构适配全球业务场景。企业无需手动干预任何细节，即可完成多语言、多币种、多时区的票据管理工作，完美适配东盟各国票据规范与业务场景。二是全球AI一键申报，打通跨境税务申报便捷通道。Tax Swift现已与20多国国税局直连，全球税务规则知识库动态更新、AI分析引擎自动扫描规则变化，联动发票识别引擎与全球交易计税规则引擎实时响应，将全球申报工作压缩成一个动作：一键登录，自动填饱，实时同步状态，可大幅提升东盟跨境贸易税务申报效率。三是全球AI税务顾问，提供全周期政策支撑。平台内置超3万条国际财税规则，覆盖200+国家税种与费金，通过实时联动发票引擎与税务引擎，实现AI自动解读、自动更新，及时识别和处置异常变化，帮助企业精准把握区域政策动态、规避合规风险，尤其针对东盟各国税务政策的更新与调整实现实时响应。三大AI能力模块的协同运作，为企业建立起全球合规洞察的能力，构筑起清晰可控的合规管理边界。当前，全球贸易格局深度调整，合规已成为企业跨境经营的核心竞争力，百望股份"贸易无国界、纳税有主权"的理念，精准契合了出海企业的合规需求。依托全球化战略布局，百望股份持续推进TaxSwift产品迭代落地，自2025年8月启动以来，产品已完成1.0版本全球电子发票布局，并在2026年加速海外数据中心与算力中心部署，加速东南亚、欧盟、中东等区域市场的拓展，向着建设覆盖80+CTC国家的全球AI票税合规平台快速演进。而东盟作为百望股份全球化出海的先锋阵地，凭借区域内旺盛的跨境贸易合规需求，成为 Tax Swift 落地应用的核心市场，已有众多企业与百望股份达成深度合作，其中越南、新加坡、印度尼西亚等东盟国家的企业、高校更是与百望携手，共同探索跨境税务合规的数智化解决方案，让 Tax Swift的技术能力与服务体系更好地适配东盟市场需求。依托中关村论坛及东盟创新合作发展论坛的开放平台，更多国际嘉宾尤其是东盟各国代表，对百望股份的数智解决方案有了进一步了解。深耕财税数智领域十余年，百望股份已经累计处理发票数量逾260亿张，对应交易总额高达1188.0万亿元，服务的纳税人识别号数量更是突破了9640万家，这些丰富的实践经验与数据智能领域的深厚沉淀，赢得了与会嘉宾产生了高度关注与广泛认可。未来，百望股份将持续深化Tax Swift平台的迭代升级，重点打磨适配东盟市场的产品能力与服务体系，打造一流的全球税务合规智能体平台，进一步拓展全球服务范围，帮助更多跨境经营的国际企业开拓发展、赢得未来！ Copyright 2026 亚太商讯 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

- Annual sales of HuaTangNing exceeded 4 million packs, a year-on-year increase of 91%, with revenues reaching RMB 492.9 million, a year-on-year increase of 93%, marking outstanding results from the Company’s fully independent commercialization operation.- Delivered record financial performance, with profit before tax reaching RMB 1,106.4 million; maintained a robust bank balance and cash position of RMB 1,092.3 million at year-end, laying a solid foundation for sustainable operations and growth.- Gross margins rose to 56.9%, and selling expenses as a percentage of revenue were optimized to 33.6% from 59.9%, significantly enhancing profitability.- HuaTangNing renewed its listing in the new National Reimbursement Drug List (NRDL) at the same price in 2025 for the calendar years 2026 and 2027, reaffirming its clinical and innovative value.- With the approval of PTE, market exclusivity in China granted another 5 years to April 2034, further strengthening commercial certainty.- Dorzagliatin was approved for commercialization in Hong Kong as HYHOMSIS®, accelerating its global expansion toward South-East Asia.- Multiple real-world evidence published to demonstrate therapeutic advantage of dorzagliatin.- Continuous expansion of therapeutic potential of glucose homeostasis and initiation of new first-in-disease indications study covering diabetes prevention, rare diseases, mild cognition impairment and frailty.SHANGHAI, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) – Hua Medicine ("the Company", Hong Kong Stock Exchange Stock Code: 2552) announces the audited consolidated results of the Company and its subsidiaries for the year ended December 31, 2025 (the “Reporting Period”). During the Reporting Period, the commercialization of HuaTangNing (dorzagliatin tablets), the Company’s core product – the global first-in-class innovative anti-diabetes medicine, glucokinase activator (GKA) – advanced comprehensively across all fronts, the Company’s independent commercialization team was efficiently and seamlessly established in its first year of operations, the Company’s R&D pipeline continued to be enriched, and the Company’s financial performance achieved a historic breakthrough, successfully entering a new stage of profitability, injecting strong momentum into the innovative development of the global diabetes treatment field.Dr. Li CHEN, Founder and CEO of Hua Medicine, stated: “2025 is a remarkable year in the commercialization operation of Hua Medicine. The Company has successfully advanced from R&D to commercialization driven organization and achieved the fully independent capacity in commercialization of global first in class novel glucose homeostasis regulator HuaTangNing. With strong market execution and product competitiveness, we have achieved nearly triple-digit growth in sales volume and revenue over 2024 when the commercialization was farmed out to sales and marketing partners. At the same time, the Company has made key progress in global market expansion through registration of drozagliatin in Hong Kong and position it toward 700 M population in south-east Asia. We continue to expand the clinical application of glucose homeostasis regulation technology and engage in new indications such as early-stage Alzheimer’s disease and Frailty. The first-in-disease efforts in GCK-MODY and Frailty set the new innovation course of Hua Medicine in the next 5 years.” Business Highlights and Operational Progress- Fully Powered Commercialization, Historic Breakthrough in ProfitabilityOn January 1, 2025, the Company assumed full responsibility for the commercialization of HuaTangNing, allowing the company to consolidate both operational and strategic control over market execution in China. The Company successfully built a professional sales team covering 10 sales regions around the country, focusing on marketing, medical affairs and commercial operation. Through an AI-empowered digital commercialization platform, operational efficiency and sales productivity were greatly enhanced, injecting new vitality into the Company’s commercial development.Reimbursement coverage under the NRDL has significantly increased accessibility, especially in Tier 2 and Tier 3 hospitals, and played a critical role in accelerating patient adoption. Since its launch in October 2022, HuaTangNing has been prescribed to over 500,000 patients through 3,000+ hospitals, community centers, pharmacies and online channels.Sales performance exceeded expectations, with 4.011 million packs of HuaTangNing sold during the reporting period, representing a 91% increase over the fiscal year 2024. This growth was achieved at the same price for both periods, underscoring strong demand and successful execution of Hua’s commercial strategy.In terms of profitability, the Company’s gross profit reached approximately RMB280.4 million, a year-on-year increase of 125%. Thanks to expanded production scale and optimized manufacturing processes, the Company’s gross margin improved to 56.9%, increasing by 8.2 percentage points as compared to 48.7% for the year of 2024. Selling expenses increased only by RMB12.3 million to RMB165.5 million, reflecting a significant positive trend towards profitability when our selling expenses in the 2025 fiscal year represents only 33.6% of revenue, whereas in the 2024 fiscal year, our selling expenses represented approximately 59.9% of revenue. In fiscal year 2025, our commercialization efforts achieved profits of approximately RMB114.9 million (as defined by gross profits less selling expenses). Although we expect to continue to increase personnel to our commercialization team, we expect this profitability trend in our commercial operations in mainland China to continue.Following the termination of the collaboration with Bayer at the end of 2024, dorzagliatin achieved a record-high sales volume. Profit before tax increased to RMB1,106.4 million for the fiscal year 2025. We ended fiscal year 2025 with a cash position of approximately RMB1,092.3 million.- Accelerated Global Layout, Strengthened Core Rights and InterestsThe Company took a key step in global expansion. On February 27, 2026, dorzagliatin (trade name: MYHOMSIS®, was successfully approved for marketing by the Hong Kong regulatory authority. The Company plans to officially launch the product in the Hong Kong market by the middle of 2026 and further expand to Asian regions. In addition, the Company submitted a new drug registration application in Macau in 2025.The Company also made new progress in intellectual property protection. In February 2026, the patent term extension (PTE) application for dorzagliatin was formally approved by the China National Intellectual Property Administration, thereby the core patent protection period of dorzagliatin extended to April 2034 and an additional 5-year market exclusivity obtained, which provides a strong guarantee for the product’s long-term market competition.In 2025, dorzagliatin was recognized as national innovation and an effective therapy for chronic diseases by the regulatory authorities in China. Accordingly, the same NRDL price was offered for the calendar years 2026 and 2027. Reimbursement coverage under the NRDL has significantly increased accessibility, especially in Tier 2 and Tier 3 hospitals, and played a critical role in accelerating patient adoption. The Company will continue to safeguard the product’s market competitiveness and patient accessibility and accelerate the popularization of the drug among patients.- Advancement of Real-World Studies, Continuous Validation of Clinical ValueReal-world evidence (RWE) studies continue to corroborate the key role of dorzagliatin in improving glucose-dependent pancreatic islet secretion function, and demonstrate its efficacy in diabetes prevention, remission, and delaying or preventing diabetes complications.The RWE study sponsored by Hua Medicine HMM0701 with 380 T2D patients was fully enrolled in 2025. The interim analysis, as reported at the 2025 American Diabetes Association (ADA), showed that 86% of such patients were taking two or more antidiabetic drugs and 41% of such patients were using insulin. After a 6-month treatment, a significant improvement of glycemic control was observed with HbA1c reduction from 8.1% to 7.3% with the mean time-in-range (TIR) levels increasing to over 70%. Thus far, the studies have demonstrated that when dorzagliatin is administered in combination with other antidiabetic drugs, such patients have experienced significantly improved post-meal glucose levels and improved β-cell function.Separately, a mechanistic study with dorzagliatin (employing double-tracer measurement) was conducted in the United States to provide scientific evidence of hepatic glycogen formation in T2D patients with an average of 17 years of diagnosed diabetes. In this study, patients were treated with dorzagliatin twice daily for 6 weeks. The results showed that dorzagliatin increased direct glucose flux to hepatic glycogen implying the improvement of restoration of hepatic Glucokinase (GK) function. Together with the clinical research data that dorzagliatin improves early phase insulin release and GLP-1 secretion, recovery of hepatic glycogen synthesis in T2D patients offers an important path in controlling post-meal glucose excursion and provides a unique opportunity in controlling diabetes complications, such as diabetes kidney diseases and mild cognition impairment.The RWE sponsored by Hua Medicine (HMM0601) has completed clinical trials with over 2,000 subjects, with average diabetes duration of 7.9 years and above 30% having disease duration more than 10 years. The initial results suggest that dorzagliatin is safe and well tolerated in Chinese T2DM patients. There were no new adverse effects observed in the study and the incident rate remains as low as what was observed in Phase III clinical trials. Patient adherence was generally high, with a mean adherence rate of approximately 95%. In this study, 80% of the participants have used one or more oral anti-diabetes medicine, and 20% used insulin. Dorzagliatin demonstrated good efficacy and safety not only in the overall population but also in elderly, obese, and hyperglycemic patient populations, whether used as monotherapy or in combination with metformin, SGLT2 inhibitors, insulin, and other medications. The topline results will be reported at the 2026 American Diabetes Association.- Deepened Clinical R&D, Continuous Expansion of New IndicationsNew Indication for Dorzagliatin – MODY-2 Patients.Medical experts in mainland China and Hong Kong have conducted independent clinical and preclinical studies of dorzagliatin for MODY-2 treatment. MODY-2, also called GCK-MODY, is a monogenic disease in which patients have a genetic defect of glucokinase gene (GCK) which results in elevated blood glucose and significant reduction of the second phase insulin secretion. The population of GCK-MODY patients is approximately 1.7 million in China. These patients are diagnosed with diabetes at a young age and represent an unmet medical need given that currently available medications are not effective. In clinical studies with MODY-2 patients, China investigators have reported that dorzagliatin is effective in reducing blood glucose levels to normal levels in MODY-2 patients who previously failed to manage their elevated blood glucose levels when treated with metformin, TZD, DPP-IV inhibitors, and SGLT-2 inhibitors. Additional results demonstrated that a single dose of dorzagliatin improved overall glucose sensitivity and second phase insulin secretion significantly in GCK-MODY patients, suggesting a unique mechanism of action of dorzagliatin to regulate GLP-1 secretion. Based on such results, Hua Medicine has communicated and reached a consensus with the CDE at NMPA to file the IND submission of dorzagliatin for MODY-2 patients in 2026.Dorzagliatin for Diabetes Prevention.Prevention of diabetes is an important focus at Hua Medicine. There are approximately 1.12 billion people living with prediabetes worldwide. We have initiated SENSITIZE 3 clinical study in Hong Kong in pre-diabetic (IGT) subjects and in early diabetes patients. These studies represent first-in-disease studies. In this double-blinded placebo-controlled study, we will evaluate the blood glucose management and pancreatic function under IVGTT and OGTT conditions to better define the clinical treatment baseline and endpoints. We expect to complete this study in 2026 and explore the opportunity to file IND applications of dorzagliatin for diabetes prevention in China and Asian Pacific regions thereafter. Dorzagliatin for Neurodegenerative Diseases.MCI shows approximately 15.5% prevalence among elderly people in China and approximately 22% in the US, and is common in T2D patients with a 45% incidence rate. The development of dorzagliatin for neurodegenerative disease is a new focus in our drug discovery efforts. Through the Genome-Wide Association Study (GWAS) and Mendelian Randomization (MR) study, we have realized the important role of GCK gene activation in the prevention of memory loss and cognitive impairment in humans. It has also come to our attention that post-meal glucose excursion is closely related to Alzheimer disease and dementia. The bio-energy balance in the brain is largely dependent on the glucose homeostasis control in the peripheral organ and the neural network communication in the central and peripheral system via spatial temporal management. Impaired glucose homeostasis and diabetes conditions result in a reduction of glucose transporter expression and insulin receptor expression in the brain, which can be prevented by low dose dorzagliatin. We have realized the potential of dorzagliatin in the treatment of mild cognitive impairment (MCI) and will initiate these first-in-disease clinical studies in the future.Dorzagliatin for Frailty.Frailty is an age-related geriatric syndrome characterized by reduced tolerance to internal and external stressors. Approximately 17% of Americans and 11% of Asians over the age of 50 suffer from frailty, while pre-frailty affects roughly 50% and 47% of these populations, respectively. It is not a single-organ disease, but the consequence of dysregulated multisystem homeostasis. Genetic evidence supports the causal effects of glucokinase (GK) activation on lowering frailty risk. We plan to initiate clinical studies in the future to advance dorzagliatin’s application in frailty.Development of combination therapy for diabetes and complications.Dorzagliatin rescues pancreatic function in glucose insulin secretion and GLP-1 secretion, as evidenced by clinical and basic research results. It also improves hepatic insulin sensitivity and reduces hepatic insulin resistance through recovery of hepatic glycogen synthesis in T2D patients. The combination of dorzagliatin with DPP-IV inhibitors, SGLT-2 inhibitors, and GLP-1 agonists have demonstrated effective regulation of lipid metabolism. Studies in combination with anticancer PI3K inhibitors have also offered unique benefits for glucose homeostasis management.- Diversified Product Pipeline, Innovative Layout for Future GrowthHua Medicine continues to enrich its pipeline layout based on core products. The Company has accelerated the R&D of a fixed-dose combination (FDC) of dorzagliatin and metformin as a twice-daily therapy for Type 2 diabetes patients with inadequate glycemic control on metformin alone, to further improve patient medication compliance. The product is supported by the strong results of the loose-dose combination in both Phase III clinical trials and real-world use. The Company has submitted an IND application to NMPA, and the GMP commercial manufacturing process has been successfully carried out, preparing for the pivotal bioequivalence study for NDA filing in 2027. Clinical studies have shown that the combination of dorzagliatin and metformin can better control blood glucose, reduce postprandial blood glucose and improve fasting blood glucose, providing new clinical value for optimizing blood glucose homeostasis endpoints.We have advanced our 2nd generation GKA as a once daily therapy for patients with obesity, leveraging dorzagliatin effects in improved glucose-stimulated GLP-1 secretion in the pancreas and in the intestine. The MAD study of the 2nd generation GKA was initiated in the United States with first-patient-in in December 2025, and we expect to report topline data by the middle of 2026.Meanwhile, the Company is also exploring combination therapy regimens of dorzagliatin with GLP-1 receptor agonists, SGLT-2 inhibitors and other drugs. In a recently published clinical trial in China, researchers reported the superior benefits of our dorzagliatin in combination with semaglutide as compared to semaglutide alone in a 12-week study. The combination group showed superior results across several key measures, including glycemic control, bodyweight related indicators and β-cell function.Financial Summary- Revenue generated by the Company was approximately RMB 492.9 million from the sale of approximately 4.011 million packs of HuaTangNing, increases of approximately 93% and 91% respectively, as compared with the year ended December 31, 2024.- Gross profit generated by the Company for the year ended December 31, 2025, was approximately RMB280.4 million, representing an increase of approximately 125%, as compared with the year ended December 31, 2024, and gross margins rose to 56.9%.- Profit before tax increased by approximately 542% to approximately RMB1,106.4 million for the year ended December 31, 2025, as compared with the year ended December 31, 2024.- Bank balances and cash position was approximately RMB1,092.3 million as of December 31, 2025.- Expenditures incurred by the Company for the year ended December 31, 2025, were approximately RMB433.4 million.Forward-Looking StatementsThis document contains statements regarding Hua Medicine's and its products' future expectations, plans and prospects. Such forward-looking statements relate only to events or information as of the date on which the statements are made in this document and are subject to change in light of future developments. Except as required by law, the Company shall not be obligated to update or publicly revise any forward-looking statements or unforeseen events after the date of such statements, whether as a result of new information, future events or other circumstances. Please read this document carefully and understand that actual future performance or results of the Company may differ materially from expectations due to various risks, uncertainties or other statutory requirements.About Hua MedicineHua Medicine (The “Company”) is an innovative drug development and commercialization company based in Shanghai, China, with companies in the United States and Hong Kong. Hua Medicine focuses on developing novel therapies for patients with unmet medical needs worldwide. Based on global resources, Hua Medicine teams up with global high-calibre people to develop breakthrough technologies and products, which contribute to innovation in diabetes care. Hua Medicine's cornerstone product HuaTangNing (dorzagliatin tablets), targets the glucose sensor glucokinase, restores glucose sensitivity in T2D patients, and stabilizes imbalances in blood glucose levels in patients. HuaTangNing was approved by the National Medical Products Administration (NMPA) of China on September 30th, 2022. It can be used alone or in combination with metformin for adult T2D patients. For patients with chronic kidney disease (CKD), no dose adjustment is required. It is an oral hypoglycemic drug that can be used for patients with Type 2 diabetes with renal function impairment. In February 2026, dorzagliatin (Trade name: MYHOMSIS®,) was approved for marketing by the Pharmaceutical Services of the Department of Health of the Government of the Hong Kong Special Administrative Region of China.For more informationHua MedicineWebsite: www.huamedicine.comInvestorsEmail: ir@huamedicine.comMediaEmail: pr@huamedicine.com Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

- 华堂宁(R)全年销量超400万盒，同比增长91%，销售额达4.929亿元，同比增长93%，公司全面自主商业化运营成效卓著。- 实现创纪录盈利，税前盈利达11.064亿元；现金余额稳健，截至年末达 10.923亿元，为持续运营发展奠定坚实基础。- 毛利率提升至56.9%，销售开支占比从59.9%优化至33.6%，盈利能力显著增强。- 华堂宁(R)原价续约新版医保目录，2026-2027年维持2025年的价格不变，临床价值和创新价值再获认可。- 随着PTE获批，中国市场独占权获5年延期至2034年4月，商业确定性进一步提升。- 多格列艾汀（HYHOMSIS(R) ，華領片(R)）获得香港地区上市批准，加速其面向东南亚的全球扩张进程。- 发布多项真实世界证据，证实多格列艾汀治疗优势。- 持续拓展血糖稳态治疗潜力，启动多项全新的疾病首创新适应症研究，研究范围涵盖糖尿病预防、罕见病、轻度认知障碍及衰弱症领域。上海, 2026年3月27日 - (亚太商讯 via SeaPRwire.com) - 华领医药（"公司"，香港联交所股份代号：2552）宣布公司及其附属公司截至2025年12月31日止年度（"报告期"）经审核的综合业绩。报告期内，公司核心产品、全球首创抗糖尿病新药、葡萄糖激酶激活剂（GKA）华堂宁(R)（多格列艾汀片）实现全方位推进，公司自主商业化团队于运营首年即实现高效组建和运转，研发管线持续丰富，财务表现实现历史性突破，成功迈入盈利新阶段，为全球糖尿病治疗领域的创新发展注入强劲动力。华领医药创始人、CEO陈力博士表示："2025年是华领医药商业化运营中的意义非凡的一年。公司成功完成从研发驱动型组织向商业化驱动型组织的转型，具备了全球首创新药、血糖稳态调节剂华堂宁(R)的完全自主商业化运营能力。凭借强劲的市场执行力与产品竞争力，相较于2024年将商业化业务委托给营销合作伙伴的阶段，公司的销量与营收实现了近三位数的增长。与此同时，通过推动多格列艾汀在香港的注册工作，公司在全球市场拓展方面取得了关键性进展，我们将向覆盖7亿人口的东南亚地区进行市场布局。我们持续拓展血糖稳态调控技术的临床应用场景，积极布局早期阿尔茨海默病、衰弱症等新适应症领域。针对GCK-MODY及衰弱症开展的疾病首创新药研发工作，将为华领医药未来五年的创新发展划定全新方向。"业务亮点与运营进展- 商业化全面发力，盈利实现历史性突破2025年1月1日起，公司正式全面接管华堂宁(R)在中国的商业化工作，获得全部运营与战略主导权，公司成功搭建了专业的销售团队，覆盖全国10个销售区域，专注于产品营销、医学事务及商业运营。通过人工智能赋能的数字商业化平台，运营效率与销售生产力大幅提升，为公司商业化发展注入新活力。受益于国家医保药品目录的持续广泛覆盖，华堂宁(R)在二级和三级医院的处方量显著增长，患者可及性不断提高，通过3000多家医院、社区卫生中心、药房和线上渠道，惠及超过50万名患者。报告期内，产品销量达401.1万盒，同比增长91%；销售额达4.929 亿元，同比增长93%，在单价保持稳定的情况下，充分印证了市场需求的强劲增长和自主商业化团队的高效执行能力。盈利能力方面，2025年，公司毛利达到2.804亿元，同比增长125%，得益于生产规模扩大及制造工艺优化，公司毛利率从2024年的48.7% 提升至56.9%，增加8.2个百分点；销售开支仅增长1230万元至1.655亿元，占收入比例优化至33.6%，较2024年的59.9%大幅下降；商业化业务实现约1.149亿元盈利（按毛利扣除销售开支计算）。公司预期仍将持续扩充商业化团队规模，但商业化运营的盈利趋势也将持续增长。在2024年底终止与拜耳合作后，多格列艾汀销售额创历史新高，报告期内，公司税前盈利增加至人民币11.064亿。截至2025年末，现金结余约为人民币10.923亿元，稳健的现金情况为公司持续发展奠定了坚实基础。- 全球布局加速推进，核心权益得到强化公司全球化布局迈出关键步伐。2026年2月27日，多格列艾汀（香港地区商品名：MYHOMSIS(R)，華領片(R)）成功获得香港监管机构的上市批准，公司计划2026年中正式在香港市场推出该产品，并将进一步向亚洲地区拓展。此外，公司已于2025年向澳门药监局递交華領片(R)（MYHOMSIS(R)）的新药上市申请。公司在知识产权保护方面也再获进展。2026年2月，中国国家知识产权局批准多格列艾汀专利期限补偿（PTE）申请，核心专利保护期延长至2034年4月，新增5年市场独占权，为产品长期市场竞争提供有力保障。2025年，多格列艾汀获中国监管机构认定为国家级创新药及慢病有效治疗药物，国家医保局已确认，2026-2027年，华堂宁(R)的国家医保目录价格维持不变，公司将持续保障产品的市场竞争力和患者可及性，尤其在二级和三级医院，加速患者的用药普及。- 真实世界研究推进，临床价值获持续验证真实世界证据（RWE）研究持续佐证多格列艾汀在葡萄糖依赖性胰岛分泌功能改善中的关键作用，并显示其在糖尿病预防、缓解及延缓或预防糖尿病并发症方面的功效。HMM0701已完成入组，共招募380名2型糖尿病患者。2025年6月，在美国ADA年会上发表的中期分析结果显示，86%的患者同时服用两种或以上降血糖药物，41%的患者使用胰岛素。经6个月治疗后，血糖控制明显改善，糖化血红蛋白由8.1%降至7.3%，平均TIR（目标范围内时间）提升至70%以上。迄今为止的研究显示，多格列艾汀与其他降糖药物联合使用时，患者的餐后血糖水平和β细胞功能均显著改善。另外，在美国进行的多格列艾汀机制研究（采用双示踪剂测量法），为平均确诊糖尿病17年的2型糖尿病患者的肝糖原生成提供了科学证据。在该研究中，患者每日服用两次多格列艾汀，持续6周。结果显示，多格列艾汀能增加葡萄糖直接流入肝糖原的通量，意味着其有助于恢复肝脏GK功能。结合临床研究数据显示，多格列艾汀可改善早期胰岛素释放和GLP-1分泌，恢复2型糖尿病患者的肝脏GK功能，不仅为控制餐后血糖波动提供重要途径，并在控制糖尿病并发症（如糖尿病肾病变及轻度认知障碍）方面提供独特契机。HMM0601研究已经完成临床试验，共纳入2000名受试者，平均患病时间为7.9年，其中超过30%患病时间超过10年。初步结果显示，多格列艾汀在中国2型糖尿病患者中安全性、耐受性良好。研究中未观察到新的不良反应，不良反应发生率维持在III期临床试验中观察到的低水平，患者的用药依从性普遍较高，平均依从率约为95%。在本研究中，80%的受试者已使用一种或多种口服降血糖药，20%的受试者使用胰岛素。多格列艾汀不仅在整体患者群体中展现出良好的疗效及安全性，在老年、肥胖及高血糖患者群体中同样有效，无论作为单药治疗或与二甲双胍、SGLT-2抑制剂、胰岛素及其他药物联合使用。顶线结果将于2026年ADA年会上发表。- 临床研发持续深化，新适应症不断拓展多格列艾汀用于治疗MODY-2患者。中国内地及香港地区医学专家已独立开展多格列艾汀用于MODY-2治疗的临床研究及临床前研究。MODY-2（又称GCK-MODY）是一种单基因疾病，患者因葡萄糖激酶基因(GCK)存在遗传缺陷，导致血糖升高及第二时相胰岛素释放显著减少。在中国，MODY-2患者群体规模约为170万人。此类患者确诊糖尿病时年龄偏小，且由于现有治疗药物疗效不佳，这一患者群体存在未被满足的医疗需求。中国研究人员在针对MODY-2患者的临床研究中报告指出，对于先前使用二甲双胍、TZD、DPP-4抑制剂及SGLT-2抑制剂仍无法控制高血糖的MODY-2患者，多格列艾汀能有效将血糖降至正常水平。其他结果显示，单剂量多格列艾汀可显著改善这类患者的整体葡萄糖敏感性及第二时相胰岛素分泌，表明多格列艾汀具有调节GLP-1分泌的独特作用机制。基于以上结果，华领医药已与国家药品监督管理局（NMPA）药品审评中心沟通，将于2026年提交多格列艾汀用于MODY-2患者的IND申请。多格列艾汀用于糖尿病预防。糖尿病预防是华领医药的重要研发重点。公司已于香港启动针对糖尿病前期糖耐量异常（IGT）受试者及早期糖尿病患者的SENSITIZE 3临床研究。这项双盲安慰剂对照研究将评估受试者在静脉葡萄糖耐量试验及口服葡萄糖耐量试验下的血糖控制及胰岛功能，以更明确界定临床治疗基线及终点指标。我们预计于2026年完成研究后，将在中国及亚太地区探索提交多格列艾汀用于糖尿病预防的IND申请的新机遇。多格列艾汀用于神经退行性疾病。研究显示，中国老年人的轻度认知障碍患病率约为15.5%，美国则约为22%；该症状在2型糖尿病患者中也相当常见，发病率达45%。多格列艾汀用于神经退行性疾病的研究已成为公司药物研发工作的新焦点。通过全基因组关联分析(GWAS)及孟德尔随机化（MR）研究，我们发现GK基因激活在预防人类记忆力衰退及认知障碍方面具有重要作用。同时我们也发现，餐后血糖波动与阿兹海默症及失智症密切相关。血糖稳态异常及糖尿病状况会导致大脑葡萄糖转运蛋白及胰岛素受体表达减少，而低剂量多格列艾汀可预防该功能损伤。我们已确认多格列艾汀在治疗轻度认知障碍方面的潜在价值，并将于未来启动针对该疾病领域的首创疗法的相关临床研究。多格列艾汀用于治疗衰弱症。衰弱症是一种与年龄相关的老年综合症，其特征为对内外应激因子的耐受性降低。约17%的美国人及11%的亚洲人（50岁以上）患有衰弱症，而处于衰弱症前期者则分别约占此两个群组的50%及47%。衰弱症并非单一器官疾病，而是多系统内稳态失调所导致的后果。遗传学证据支持GK激活对降低衰弱症风险具有因果作用。我们计划于未来启动临床研究，以推进多格列艾汀在衰弱症治疗领域的应用。联合用药用于糖尿病及并发症的治疗。临床与基础研究结果显示，多格列艾汀能恢复胰腺在葡萄糖刺激下的胰岛素及GLP-1分泌，也可以通过恢复2型糖尿病患者肝脏葡萄糖激酶功能，改善肝脏胰岛素敏感性并降低肝脏胰岛素抵抗。多格列艾汀与DPP-4抑制剂、SGLT-2抑制剂及GLP-1受体激动剂的联合使用已证明可有效调节脂质代谢，与抗癌PI3K抑制剂联合使用的研究也为血糖稳态管理带来独特优势。- 产品管线丰富多元，创新布局未来增长华领医药在核心产品基础上持续丰富管线布局。依托多格列艾汀与二甲双胍联合用药在III期临床试验和真实世界应用中取得的优异数据，公司加速推进多格列艾汀与二甲双胍固定复方制剂（FDC）的研发。该制剂为每日两次给药方案，适用于单用二甲双胍血糖控制不佳的2型糖尿病患者，旨在以进一步提升患者的用药依从性。公司已向NMPA提交IND申请文件。此外，GMP商业化生产工艺也已成功开展，为2027年新药上市申请的关键生物等效性研究做好准备。临床研究显示，多格列艾汀与二甲双胍联用能够更好地控制血糖，降低餐后血糖，改善空腹血糖，为优化血糖稳态终点提供了新的临床价值。第二代GKA的研发取得重要突破。作为肥胖2型糖尿病患者每日一次治疗的缓释新片剂，公司已在美国启动多格列艾汀多剂量递增（MAD）研究，以探讨第二代GKA在血糖稳态控制方面的疗效及新药的作用机制，首例患者已于2025年12月入组，预计2026年中公布顶线数据。同时，公司还在探索多格列艾汀与GLP-1受体激动剂、SGLT-2抑制剂等药物的联合治疗方案。近期，在一项中国的临床试验中，研究者报告：多格列艾汀联合司美格鲁肽治疗12周，疗效显著优于司美格鲁肽单药治疗。联合治疗组在血糖控制、体重相关指标及β细胞功能等多项关键指标上均表现更优。财务摘要截至2025年12月31日，- 华堂宁(R)全年销量约401.1万盒，相较2024年全年，同比增长91%，实现营收约4.929亿元，同比增长93%。- 毛利约人民币2.804亿元，同比增长125%，毛利率提升至56.9%；- 税前盈利约人民币11.064亿元，较2024年增长542%；- 银行结余及现金约人民币10.923亿元，资金状况稳健；- 总开支约人民币4.334亿。前瞻性声明本文包含有关华领医药以及产品未来预期、计划和前景的陈述。该等前瞻性陈述仅与本文作出该陈述当日的事件或资料有关，可能因未来发展而出现变动。除法律规定外，于作出前瞻性陈述当日之后，无论是否出现新资料、未来事件或其他情况，我们并无责任更新或公开修改任何前瞻性陈述及预料之外的事件。请仔细阅读本文并理解，由于各种风险、不确定性或其他法定要求我们的实际未来业绩或表现可能与预期有重大差异。关于华领华领医药（"本公司"）是一家总部位于中国上海的创新药物研发和商业化公司，在美国、中国香港设立了公司。华领医药专注于未被满足的医疗需求，为全球患者开发全新疗法。华领医药汇聚全球医药行业高素质人才，融合全球创新技术，依托全球优势资源，研究开发突破性的技术和产品，引领全球糖尿病医疗创新。公司核心产品华堂宁(R)（多格列艾汀片）以葡萄糖传感器葡萄糖激酶为靶点，提升2型糖尿病患者的葡萄糖敏感性，改善患者血糖稳态失调。2022年9月30日，华堂宁(R)已获得中国国家药品监督管理局（NMPA）的上市批准，用于单独用药或者与二甲双胍联合用药，治疗成人2型糖尿病。对于肾功能不全患者，无需调整剂量，是一款可用于肾功能损伤的2型糖尿病患者的口服降糖药物。2026年2月，多格列艾汀（商品名：MYHOMSIS(R)，華領片(R)）获得中国香港特别行政区政府卫生署药物办公室的上市批准。详情垂询华领医药网址：www.huamedicine.com投资者电邮：ir@huamedicine.com媒体电邮：pr@huamedicine.com新闻免责声明本材料，如为上下文论述的准确性和完整性，提及在中国上市的产品相关信息的，特别是标识或要求，应遵循中国监管机构批准的相关文件。另外，相关信息不应被解读为对任何药物或者诊疗方案的推荐或者宣传，亦不应替代任何医疗卫生专业人士的医疗建议，涉及医疗的相关事宜务必咨询医疗卫生专业人士。 Copyright 2026 亚太商讯 via SeaPRwire.com. 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HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) – 26 March, Unisound (09678.HK) announced its audited annual results for the year ended December 31, 2025. As the Company's first annual results announcement since listing, it underscores strong growth momentum and continued improvement in its financial profile.Revenue Mix Continues to Improve, with Faster Growth in H2For the full year of 2025, Unisound achieved total revenue of $175 million, representing a year-on-year (YoY) increase of 29%. Revenue in the second half of the year increased by 33% YoY to $117 million.It is worth noting that the Company's large language model (LLM) business generated a full-year revenue of $88.43 million, surging by over 10 times YoY. In particular, this business contributed approximately $72.49 million in H2 revenue, five times the level recorded in H1, demonstrating a compelling capacity for large-scale commercial application.Losses Narrowed Significantly, Making the Path to Profitability Increasingly ClearAlongside the rapid revenue growth, the Company's losses improved markedly. In the second half of 2025, the Company's net loss narrowed by 84% YoY, and its adjusted loss narrowed by 92% YoY, approaching break-even. This reflects the Company's ongoing improvements in cost control and operational efficiency.Simultaneously, some of the Company's operating metrics saw marked improvement. The adjusted expense ratio declined significantly by 10 percentage points YoY, while selling expenses decreased rather than increased and accounted for only 5.4%, highlighting a clear improvement in cost-to-efficiency ratio. In 2025, revenue per employee reached $365,300, up 25% YoY from $292,900 in 2024. Employee productivity continued to lead the industry, clearly underscoring the Company's core strengths in technology-driven, lean operations.Dual-Engine Strategy Gains Traction, with AI in Healthcare and AI in Daily Life Advancing in TandemIn 2025, driven by both technological breakthroughs and policy tailwinds, global demand for AI continued to rise. Unisound adhered to its "Strong Foundation Model + Deep Application" strategy, continued to strengthen its multimodal technology foundation, and drove the continuous elevation of the global influence of its proprietary large model matrix in fields such as healthcare, speech, and OCR.On the commercialization front, the Company leveraged its AI-native organization to accelerate business execution, and its dual-engine strategy in AI in Healthcare and AI in Daily Life delivered notable results. During the reporting period:The AI in Daily Life business achieved revenue of $140 million, a YoY increase of 30.8%. Among this, the Transportation segment recorded nearly 40% YoY growth. At present, AI agent applications based on the Shanhai large model have been deployed in more than 10 cities, including Qingdao, Ningbo, Shenzhen and Nanning. In addition, cumulative AI chip shipments exceeded 110 million units, further validating the Company's scale capabilities in endpoint AI products.The AI in Healthcare business achieved revenue of $35.38 million, a YoY increase of 22.3%, with average revenue per customer growing by 53.2% YoY. In 2025, over 70% of the hospitals the Company collaborated with were tertiary hospitals, and more than one-third of customers had maintained continuous cooperation for over three years. The medical-record entry and generation products powered by the medical large model delivered a 10-fold YoY increase in full-annual medical record generation at a single campus of a leading Class III hospital. The commercial insurance AI agent platform recorded a 37-fold YoY increase in case processing volume. In deep cooperation with a leading insurance group, the expense control rate was effectively raised to approximately 20%, delivering more than $145 million in incremental cost management compared with traditional review methods, comprehensively empowering insurance institutions to refine their medical risk management operations.Continued R&D Investment Strengthens the Technology MoatTo consolidate its industry-leading position, the Company continued to invest heavily in R&D in 2025. Full-year R&D expenses exceeded $55.09 million, accounting for 75% of the Company's adjusted operating expenses, while R&D personnel accounted for 69% of the total workforce. This sustained investment drove breakthroughs across multiple technology areas. For example, in the MedBench 4.0 evaluation, the Company ranked first place in three technical paradigms: "Medical AI Agent," "Medical Large Language Model," and "Medical Multimodal Large Model," earning a "Triple Crown."Outlook: Deepening the Technological Foundation and Expanding Application BoundariesLooking ahead, Unisound will continue to deepen its "Strong Foundation Model + Deep Application" strategy. On the technological front, the Company will continue to increase strategic investment in foundational large models and strive to maintain a world-class level. On the application front, it will use the large-scale expansion of MaaS (Model-as-a-Service) and AI agents as its core growth engine, driving exponential growth in its AI in Daily Life and AI in Healthcare businesses. Meanwhile, the Company is actively exploring the establishment of a recurring revenue system through models such as API calls and Token-based billing, and regards opportunities in consumer-facing (C-end) products as a second growth curve to further expand its commercialization boundaries.Between Q2 and Q3 2026, Unisound will launch a native AI agent large model for programming and office applications, which is expected to double both intelligence density and token production efficiency. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com